Acetazolamide is a diuretic class of drugs that can be used to prevent and reduce altitude sickness symptoms, such as headaches, fatigue, dizziness, vomiting, and shortness of breath. This symptom is usually experienced by someone who climbs to a plateau (above 3,000 meters above sea level) at a speed that is too fast.

When climbing is done too fast, the body does not have enough time to adapt to air pressure and low oxygen levels at altitude. This causes a leak of fluid in the capillary arteries. This fluid will spread to the brain, lungs, and other parts of the body, accumulate, to eventually cause symptoms of altitude sickness. Acetazolamide works by reducing the buildup of the liquid.

In addition, acetazolamide can be combined with other drugs to treat glaucoma and control seizures in epilepsy.

Trademark: Glauseta

About Acetazolamide
Group: Diuretic
Category: Prescription Drug


  • Prevent and relieve symptoms of altitude sickness.
  • Dealing with glaucoma and epilepsy.

Consumed by: adults
Category C pregnancy and lactation: Studies in animal studies show side effects on the fetus, but there are no controlled studies in pregnant women. The drug should only be used if the expected amount of benefit exceeds the risk to the fetus.

Acetazolamide can be absorbed into breast milk, may not be used during breastfeeding.
Form medicine: Tablet


  • Be careful using acetazolamide if you have or are experiencing hypokalemia, hyponatremia, acidosis, liver disorders, kidney disorders, cirrhosis, chronic obstructive pulmonary disease, emphysema, and diabetes.
  • Tell your doctor if you are taking other drugs, especially sulfonamide antibiotics and aspirin.
  • The use of acetazolemide in elderly patients should be with the advice and supervision of a doctor.
  • Avoid driving or operating machinery while undergoing treatment with acetazolamide, because this drug can cause drowsiness.
  • This drug can reduce potassium levels in the body. During treatment, multiply eating foods or drinks that contain lots of potassium, such as bananas or orange juice.
  • If an allergic reaction or overdose occurs after taking acetazolamide, see a doctor immediately.

Acetazolamide dose

The Acetazolamide dose varies for each patient. The following are common doses of Acetazolamide for several conditions:

Prevent and relieve symptoms of altitude sickness
Adults: 500-1000 mg per day, which is divided into several consumption schedules. It is recommended to take 1-2 days before climbing. If needed, it can be continued for 2 days while in the highlands.

Epilepsy and glaucoma
Adults: 250-1000 mg per day, which is divided into several consumption schedules. Can be taken as a single drug or in combination with other drugs.
Children over 12 years: 8-30 mg / kg, in doses divided into several consumption schedules. The maximum dose is 750 mg per day.

Adults: 230-375 mg, once a day.

Take Acetazolamide Correctly

In taking acetazolamide, follow the doctor’s advice and read the instructions printed on the drug packaging.

Acetazolamide can be consumed before or after meals.

Be sure to take acetazolamide at the same time every day, so that the treatment results are maximal. For patients who forget to take acetazolamide, it is recommended to do it immediately as soon as they remember, if the next consumption schedule is not too close. If it’s close, ignore it and don’t double the dose.

See a doctor immediately if symptoms don’t improve.

Drug Interactions

The following are interactions that can occur when using acetazolemide with other drugs:

  • Increases blood phenytoin levels and the risk of osteomalacia.
  • Potentially increasing the side effects of antifolate drugs, such as pyrimethamine.
  • Can reduce the effectiveness of lithium.
  • Increases the risk of kidney stones, if taken with sodium bicarbonate.
  • Increase the levels of the drug ciclosporin in the blood.
  • Increases the risk of anorexia, acidosis, coma, or death, if taken with high-dose aspirin.

Recognize Side Effects and Dangers of Acetazolamide

Side effects that may arise after consuming acetazolamide are:

  • Sleepy
  • Confusion
  • Anorexia
  • Seizures
  • Tingling
  • Sensitive to sunlight
  • Limp
  • Paralysis

See more about:

  • Epilepsy
  • Glaucoma

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